Managing Arterial Stiffness: The Role of ACE Inhibitors, ARBs, and Natural Alternatives
Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are widely used medications that offer significant benefits for arterial stiffness, a crucial factor in cardiovascular health.
Mechanisms of Action
1. Renin-Angiotensin System (RAS) Modulation:
– ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a strong vasoconstrictor. This reduction in angiotensin II leads to vasodilation and lower blood pressure (McMurray & Pfeffer, 2005).
